Molecular Dynamics Simulation of Water Transportation through Aquaporin-4 in Rat Brain Cells

نویسندگان

  • A. R. Illchani -
  • F. Kaveh -
  • K. zare -
  • N. Khodayari -
  • S. Salemi -
چکیده مقاله:

This paper investigates the mechanism of water transportation through aquaporin-4(AQP4) of ratbrain cells by means of molecular dynamics simulation with CHARMM software. The AQP4 wasembedded into a bilayer made of Dimystroilphosphatylcholine (DMPC). The results illustrate thatwater molecules move through AQP4's channel with change of orientation of oxygen of eachwater molecule.

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molecular dynamics simulation of water transportation through aquaporin-4 in rat brain cells

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عنوان ژورنال

دوره 5  شماره 4

صفحات  1- 6

تاریخ انتشار 2009-02-01

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